Welcome to the HCSD (Human Cancer Secretome Database)
The HCSD can be used to Query publicly available proteomics data published in the field of cancer secretome and tumor microenviroment.
Compare measurements from different proteomics studies.
Retrieve annotation and cross-references in both gene and protein level for each data points.
Visualize the predicted secretory features and post-translational modification sites (PTMs) for each protein.
How to use HCSD
1- Go to the QUERY menu
2- In the quick search section, use dynamic data tables to explore the data from the label-free or the label-based proteomics studies. The tables are interactive and you can sort and/or filter any column of interest.
3- For mote detail query, when you have a gene of the interest (of from quick search), use advanced search. It allows you to get details data for encoded protein that is detected and quantified in various cancer types in the collected studies. In addition, you will get annotation,cross references, experimental design, validation, and secretory features data.
About the database
HCSD updated: 2015-05-14
21 label-free study
14 label-based study
73 tissue and cell line samples.
Amir Feizi, Amir Banaei-Esfahani, and Jens Nielsen. HCSD: the human cancer secretome database. Database 2015: bav051 doi:10.1093/database/bav051 published online June 14, 2015